Solubility of gemcitabine hydrochloride

Author: myto

August undefined, 2024

WebApr 10, 2024 · Erlotinib’s aqueous solubility is pH-dependent; it is less soluble at neutral pH but more soluble at acidic pH (~ below 5). Erlotinib HCl, marketed under the brand name Tarceva, is prescribed as a single film-coated orally administered tablet at strengths of 25–125. Erlotinib HCL has a maximum solubility of around 0.4 mg/mL at a pH of ~ 2 .

Gemcitabine: Package Insert - Drugs.com

WebGemcitabine prepared as intravenous admixtures of 0.1 and 10 mg/mL as the hydrochloride salt in 5% dextrose injection and 0.9% sodium chloride injection in PVC bags and as a … WebGemcitabine HCl (Gemzar) ... *<1 mg/ml means slightly soluble or insoluble. *Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and … nail\\u0026beauty anfang ネイルアンドビューティーアンファング

Gemcitabine C9H11F2N3O4 - PubChem

WebUse in Cancer. Gemcitabine hydrochloride is approved to be used alone or with other drugs to treat: Breast cancer that cannot be treated with or that did not respond to … WebTest conditions included (1) reconstituted gemcitabine at a concentration of 38 mg/mL as the hydrochloride salt in 0.9% sodium chloride or sterile water for injection in the original … WebName Gemcitabine hydrochloride Drug Entry Gemcitabine. Gemcitabine is a nucleoside analog and a chemotherapeutic agent. It was originally investigated for its antiviral … nailiss ネイリス大阪市時間

Polymers Free Full-Text Local Delivery of Antiproliferative …

WebJun 1, 2024 · Gemcitabine hydrochloride is soluble in water, slightly soluble in methanol, and practically insoluble in ethanol and polar organic solvents. Gemcitabine for Injection, … WebJun 1, 2024 · Gemcitabine hydrochloride is soluble in water, slightly soluble in methanol, and practically insoluble in ethanol and polar organic solvents. Gemcitabine for Injection, USP is a sterile white to off-white lyophilized powder and available as 200 mg and 1 g single-dose vials for intravenous use only. nail 意味スラングWebApplication. It is intended to be used as a USP reference standard in specified quality tests and assays. Also used to prepare standard solutions in the assay and impurities analysis … nailclinique ネイルクリニーク福岡店

"WebMar 1, 2024 · One vial contains Gemcitabine hydrochloride equivalent to 200 mg Gemcitabine One vial contains Gemcitabine hydrochloride equivalent to 1000 mg Gemcitabine . After reconstitution, the solution contains 38 mg/ml of Gemcitabine. Excipients: Each 200 mg vial contains 3.5 mg (<1 mmol) sodium. Each 1,000 mg vial … " - Solubility of gemcitabine hydrochloride

Solubility of gemcitabine hydrochloride

Polymers Free Full-Text Local Delivery of Antiproliferative …

WebGemcitabine (LY-188011, NSC 613327) HCl is a DNA synthesis inhibitor with IC50 of 50 nM, 40 nM, 18 nM and 12 nM in PANC1, MIAPaCa2, BxPC3 and Capan2 cells, respectively. … WebGemcitabine, HCl - CAS 122111-03-9 - Calbiochem. View Price and Availability. Supelco. PHR2582. Gemcitabine hydrochloride. Pharmaceutical Secondary Standard; Certified …

Did you know?

WebApr 1, 1999 · Reconstituted gemcitabine as the hydrochloride salt in the original vials is chemically stable at room temperature for 35 days but may develop crystals when stored … WebGemcitabine Hydrochloride is the hydrochloride salt of an analogue of the antimetabolite nucleoside deoxycytidine with antineoplastic activity. …

WebGemcitabine hydrochloride (2′-Deoxy-2′,2′-difluorocytidine; dFdC ); >= 98% HPLC; This compound is a featured product for Apoptosis research; Gemcitabine is a widely used … WebNov 25, 2024 · The empirical formula for gemcitabine HCl is C 9 H 11 F 2 N 3 O 4 • HCl. It has a molecular weight of 299.66. Gemcitabine HCl is soluble in water, slightly soluble in …

WebGemcitabine is a chemotherapeutic agent used as monotherapy or in combination with other anticancer agents. In combination with [carboplatin], it is indicated for the treatment … WebApr 1, 1999 · Gemcitabine is a fluoro-cytidine analog with primarily antitumor activity and is administered intravenously [120]. Although its hydrochloride salt is well soluble in water …

WebGemcitabine hydrochloride (2′-Deoxy-2′,2′-difluorocytidine; dFdC ); >= 98% HPLC; This compound is a featured product for Apoptosis research; Gemcitabine is a widely used antineoplastic agent and antimetabolite; Gemcitabine is a widely used antitumor agents in both clinics and research labs;

WebJun 29, 2024 · Gemcitabine 1 g/m 2 (as 30-minute infusion) has been given on days 1 and 8 of each 21-day cycle; administered in combination with cisplatin (25 mg/m 2 as 1-hour … naility ビルダージェルhttp://shiji.cnreagent.com/s/sv273316.html nailist ネイリストWebGeneral description. A bioavailable, moderately toxic, deoxyctytidine analog with anti-metabolite and anti-tumor properties. Shown to be effective against a variety of tumors … naility ステップレスジェルWebDec 2, 2013 · The release behavior of another anti-cancer drug gemcitabine from the PU matrix is quite different from that of PTX due to the extreme difference in water solubility between gemcitabine and PTX.PTX is practically insoluble in water, whereas gemcitabine is readily soluble in water and has a solubility of 1.55% [37,67]. naileyelush jolie 【ネイル\u0026アイラッシュジョリー】あべの/天王寺WebFeb 25, 2024 · The solution was then diluted 10× with a premade PBS solution of gemcitabine (hydrochloride salt) (12.65 mg/mL). Final concentrations of drugs were 10/1 mg/mL GT. CrEL drug suspensions were used within the same day of preparation due to instability. ... Whether a water soluble gemcitabine (Log P=−1.5) and insoluble paclitaxel ... naility イージーフォームWebSolubility: Soluble in DMSO at 12.5 mg/mL with slight warming; very poorly soluble in ethanol; soluble in water at 25 mg/mL with slight warming; buffers, ... Gemcitabine … nailed 意味スラングWebGemcitabine hydrochloride (2′-Deoxy-2′,2′-difluorocytidine; dFdC ); >= 98% HPLC; This compound is a featured product for Apoptosis research; Gemcitabine is a widely used … nai tl シンチレータアクチベータ